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ADPN

Adiponectin(ADPN) is a protein hormone that is express and secreted by adipose tissue. It's abundant in the blood circulation, About 0.01% of total human plasma protein. It plays an important role in regulating insulin sensitivity and glucose metabolism.

Human adiponectin monomer is composed of 244 amino acids, including four regions: N-terminal signal peptide, non-homologous region, collagen repeat sequence and globular carboxyl-terminal. Collagen repeat sequence has great correlation with the evolution of species. Adiponectin occurs in the blood in many subtypes, Monomer adiponectin (28kDa) is first polymerized into biologically active trimer (65 kDa) in adipocytes, and then on this basis into hexamer (150 kDa) and high molecular weight asymmetric bouquet like adiponectin (18-36 monomers, >280 kDa) and secreted into the circulating blood.The plasma adiponectin properties of normal subjects were stable, and several subtypes of adiponectin did not convert to each other.

Adiponectin is a novel predictor of early risk for type 2 diabetes.Adiponectin is a risk predictor of diabetes, unlike blood glucose and glycosylated hemoglobin, Adiponectin can be used to screen out people at high risk of diabetes with normal blood glucose but abnormal physiological metabolism. Adiponectin can dynamically reflect the level of insulin resistance of the body and is closely related to the metabolic health of individuals.

Catalog Product Name Type Function Application
CSB-DA120AmN② Mouse anti-human Adiponectin(ADPN) monoclonal antibody Monoclonal Antibodies
Cardiovascular Disease
ELISA and other possible application
CSB-DA120AmN① Mouse anti-human Adiponectin(ADPN) monoclonal antibody Monoclonal Antibodies
Cardiovascular Disease
ELISA and other possible application
CSB-DP120B Human Adiponectin protein Antigens
Cardiovascular Disease
Calibrator or standard in ELISA and other possible application
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