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CysC

Cystatin-C (CYSC) is a non-glycosylated, low molecular weight, cation protein that is regularly synthesized by most nucleated cells. Cystatin-C is an endogenous protein that is known to be affected little by age, race, and muscle mass. It is not only used as a biomarker of renal function but also has positive associations with obesity, insulin resistance, hypertension, and cardiovascular mortality. Higher levels of serum cystatin-C were associated with increased prevalence of diabetic conditions.

Under normal circumstances, cystatin C in serum is 0.47-1.09 mg/L. When renal function is impaired, cystatin C concentration in blood will change with GFR. In renal failure, GFR decrease while cystain C concentration in blood can increase more than 10 times. Under normal glomerular filtration rate and renal tubules dysfunction can hinder cystatin C absorption and its rapid decomposition in the renal tubules, increasing its concentration in urine over 100 times.

Catalog Product Name Type Function Application
CSB-DA004AmN③ Mouse anti-human Cystatin-C protein(CysC) monoclonal antibody Monoclonal Antibodies
Renal Function & Injury
ELISA, CLIA, LFIA
CSB-DA004AmN② Mouse anti-human Cystatin-C protein monoclonal antibody Monoclonal Antibodies
Renal Function & Injury
ELISA, CLIA, LETIA and other possible application
CSB-DA004AmN① Mouse anti-human Cystatin-C protein monoclonal antibody Monoclonal Antibodies
Renal Function & Injury
ELISA, CLIA, LETIA and other possible application
CSB-DP004A Human Cystatin-C protein Antigens
Renal Function & Injury
Calibrator or standard in ELISA, latex enhanced turbidimetricimmunoassay (LETIA) and other possible application.
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