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RBP4

Retinol Binding Protein 4(RBP4)belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Retinol-binding protein 4 has recently been described as an adipokine that contributes to insulin resistance in the AG4KO mouse model. It is secreted by adipocytes, and can act as a signal to other cells, when there is a decrease in plasma glucose concentration.Mutations in the RBP4 gene have recently been linked to a form of autosomal dominant microphthalmia, anophthalmia, and coloboma (MAC) disease.

Catalog Product Name Type Function Application
CSB-DA002AmN② Mouse anti-human Retinol-binding protein 4 (RBP4) monoclonal antibody Monoclonal Antibodies
Renal Function & Injury
ELISA , LETIA
CSB-DA002AmN① Mouse anti-human Retinol-binding protein 4 (RBP4) monoclonal antibody Monoclonal Antibodies
Renal Function & Injury
ELISA , LETIA
CSB-DP002A Human Retinol-binding protein 4 Antigens
Renal Function & Injury
Calibrator or standard in ELISA, latex enhanced turbidimetricimmunoassay (LETIA), chemiluminescent Immunoassay (CLIA) and other possible application
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