mRNA Vaccine Related Enzymes
Enzymes used in mRNA vaccine preparation are the key raw materials in the production of mRNA vaccines and drugs. The production and development process of mRNA drugs includes: 1) sequencing and analysis to confirm key proteins; 2) Construct the plasmid and transform it into Escherichia coli and multiply it to achieve the purpose of plasmid expansion, extract the plasmid and purify it; 3) digestion linearization; 4) In vitro transcription, cap and tail; 5) Liposome encapsulation and purification. This process involves restriction endonucrenase, RNA polymerase, capping enzyme and Poly(A) polymerase, which are all essential raw materials in the production of mRNA vaccines and drugs. Gmp-grade mRNA raw material enzymes All products are produced with medicinal specifications of raw materials, strictly control host protein residues, nucleic acid residues, etc., in line with GMP standards of product production and quality management regulations.